Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ASAH1 in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]